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Molecular mechanism for stress-induced depression assessed by sequencing miRNA and mRNA in medial prefrontal cortex. Molecular mechanism for stress-induced depression assessed by sequencing miRNA and mRNA in medial prefrontal cortex

NIAID Data Ecosystem2026-03-09 收录

抑郁症分子机制

前额叶皮层转录组

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA322051 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2016-05-18

星形胶质细胞转录组

抑郁症分子机制

Major Depression (MDD) is a prevalent psychiatric disorder and exposure to stress is robust risk factor for MDD. Clinical data and rodent models have indicated the negative impact of chronic stress in

NIAID Data Ecosystem40

Gene expression microarray analysis on the medial prefrontal cortex of wild-type mice (2W and 12W)

前额叶皮层转录组

年龄相关基因表达

The gene expression patterns in the medial prefrontal cortex of wild-type mice (2W and 12W) were examined using Affymetrix GeneChip arrays. Medial prefrontal cortex RNA isolated from C57BL/6J mice (2W

NIAID Data Ecosystem30

Table_5_miR-30 Family miRNAs Mediate the Effect of Chronic Social Defeat Stress on Hippocampal Neurogenesis in Mouse Depression Model.pdf

抑郁症分子机制

神经发生

Depression is a debilitating psychiatric disorder with a high rate of relapse and a low rate of response to antidepressant treatment. There is a dearth of new antidepressants due to an incomplete unde

NIAID Data Ecosystem20

m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients. m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients

RNA表观遗传学

抑郁症分子机制

N6-Methyladenosine (m6A) and N6,2′-O-dimethyladenosine (m6Am) are abundant mRNA modifications that regulate transcript processing and translation. The role of both, here termed m6A/m, in the human str

NIAID Data Ecosystem40

Table_6_miRNA and mRNA Profiles in Ventral Tegmental Area From Juvenile Mice With Companion Communication of Improving CUMS-Induced Depression-Like Behaviors.XLS

抑郁症分子机制

奖赏回路研究

Under chronic stress, the appearance of depression-like behaviors may be related to the decline of the brain's reward circuit function which caused by long-term lack of reward. However, the effect of

NIAID Data Ecosystem30

Molecular mechanism for stress-induced depression assessed by sequencing miRNA and mRNA in medial prefrontal cortex. Molecular mechanism for stress-induced depression assessed by sequencing miRNA and mRNA in medial prefrontal cortex

资源简介：

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