Effective reproduction number and strength of infection according to major health region and epidemiological week, Minas Gerais, Brazil, 2016 to 2018.

Three- to seven-week periods were selected with increases in cases, normally identified at the start of the outbreak in each of the macroregions. The macroregions in the bold face presented statistically significant values (p value < 0.05) in the regression that estimated the rate of growth of cases. The macroregions Norte, Jequitinhonha, Triângulo do Norte, and Triângulo do Sul did not display upward curves, thus preventing calculation of the reproduction number in these regions.