Associations of validated CHD loci with incident coronary heart disease in African Americans.

Abbreviations: LD, linkage disequilibrium; SNP, single nucleotide polymorphism; AA, African Americans from PAGE studies; NA, not available. Only SNPs with minor allele frequency>0.01 that passed quality control are included. Linkage disequilibrium in African Americans was calculated in the ARIC study and allele frequencies from the ARIC and WHI genotyped data. Thresholds for significant associations for SNPs with LD r2*proxy of rs1760994,†proxy of rs4977574. Between-study heterogeneity was not significant (pNature Genetics. 45(1): 25–33.Associations of validated CHD loci with incident coronary heart disease in African Americans.