Type 2 innate lymphoid cells (ILC2s) play a pivotal role in type 2 asthma. CD226 is a costimulatory molecule involved in various inflammatory diseases. Here, we aimed to investigate CD226 expression a

NIAID Data Ecosystem40

Additional file 1: of Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics

病毒学

哮喘病理机制

Figure S1. Monolayer cultures and generation of ALI-pBEC cultures from non-asthmatics and asthmatics. Figure S2. Viability of HBEC6-KT cell after IAV H1N1 infection at different MOIs. Figure S3. Respo

DataCite Commons2020-08-28 更新10

IL-33 induces an antiviral signature in mast cells but enhances their permissiveness for human rhinovirus infection

病毒-宿主相互作用

哮喘病理机制

Mast cells (MCs) are classically associated with allergic asthma but their role in antiviral immunity is unclear. Human rhinoviruses (HRVs) are a major cause of asthma exacerbations and can infect and

NIAID Data Ecosystem40

IMPACT OF AGING ON THE DEVELOPMENT OF ASTHMA PHENOTYPES

哮喘病理机制

年龄依赖性免疫反应

Asthma is the most common chronic disease of childhood, in which infectious and allergic agents trigger airway inflammation leading to respiratory symptoms. Although generally viewed as a life-long di

NIAID Data Ecosystem10

gut clostridiales regulates airway inflammation via modifying acetate production in allergic asthma

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