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Quality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1

ChEBI2013-12-04 更新2026-07-21 收录

RNA剪接质量控制

SR蛋白功能研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-52808 数据链接链接失效反馈

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资源简介：

Quality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1

应用场景：

创建时间：

2013-12-04

RNA剪接质量控制

核质运输调控

Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature RNAs associate wi

NIAID Data Ecosystem50

Structure of an aberrant spliceosome intermediate on its way to disassembly

剪接体结构

RNA剪接质量控制

Intron removal during pre-mRNA splicing is of extraordinary complexity and its disruption causes a vast number of genetic diseases in humans. While key steps of the canonical spliceosome cycle have be

NIAID Data Ecosystem10

Structure of an aberrant spliceosome intermediate on its way to disassembly. Structure of an aberrant spliceosome intermediate on its way to disassembly

剪接体结构

RNA剪接质量控制

NIAID Data Ecosystem00

Quality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1. Saccharomyces cerevisiae

RNA剪接质量控制

RNA动态监测

NIAID Data Ecosystem20

RNAi profiling by array of mouse P19 cells to investigate how SR proteins coordinate gene expression programs

SR蛋白功能研究

基因表达调控