(A) Schematic of the extended mathematical model. The inhibition of virus replication by early IFN signals is described explicitly. For further details see legend to Fig 6A. (B) Extent of predicted vi
S3B Fig. Mitochondrial DNA is the likely cGAS ligand during lytic KSHV infection. BC-3 cells were treated with or without 20 μM dideoxycytidine (“ddC”) for 48 hours to deplete mitochondrial DNA (“mtDN
