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Induction of pluripotency in mouse somatic cells with novel factors

ChEBI2013-05-28 更新2026-07-21 收录

体内重编程

诱导多能干细胞

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43995 数据链接链接失效反馈

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资源简介：

Induction of pluripotency in mouse somatic cells with novel factors

应用场景：

创建时间：

2013-05-28

脊髓小脑性共济失调

诱导多能干细胞

A collection of four induced pluripotent stem cell models (iPSC) derived from patients diagnosed with Spinocerebellar ataxia 15 (SCA15) . Spinocerebellar ataxia 15 (SCA15) is a neurological condition

NIAID Data Ecosystem90

Global Regulatory Network Controlling Human Somatic Cell Reprogramming [SMAD3 and SFRS11 Knockdown]. Homo sapiens

体内重编程

转录调控网络

This is the first study deciphering the global regulatory network that drives human somatic cells during epigenetic rewiring towards the pluripotent state. Overall design: Examination of the Transcrip

NIAID Data Ecosystem70

Function of Sox2 and Klf4 during SKM reprogramming

诱导多能干细胞

转录因子功能分析

Differentiated somatic cells can be reprogrammed into induced pluripotent stem cells by ectopic expression of transcription factors Oct4, Sox2, Klf4, and c-Myc, but the mechanisms are still to be diss

NIAID Data Ecosystem50

Heterochromatin lossening by Oct4 in somatic cell reprogramming

染色质重塑

体内重编程

The success of Yamanaka factor reprogramming mouse embryonic fibroblasts (MEFs) into induced pluripotent stem cells (iPSCs) suggests that some factor(s) must remodel the nuclei from a condensed state

NIAID Data Ecosystem80

Mus musculus Raw sequence reads

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基因表达调控

NAC1 regulates somatic cell reprogramming by controlling E-cadherin expression.Null hNAC1 (S2)

NIAID Data Ecosystem60