mathys_et_al_2019_reprocessed_count_matrix

An single-cell object (SCE) with extension .qs of the Mathys et al., 2019 study data - https://doi.org/10.1038/s41586-019-1195-2 into Single-nucleus transcriptomic analysis and differential expression (DE) of Alzheimer’s disease. The data has been processed with scFlow -https://www.biorxiv.org/content/10.1101/2021.08.16.456499v2 . Note this includes the processed count matrix and associated metadata.The samples were single-nucleus transcriptomes from the prefrontal cortex of 48 individuals, 24 of which had high levels of β-amyloid and other pathological hallmarks of AD (‘AD-pathology’), and 24 individuals with no or very low β-amyloid burden or other pathologies (‘no-pathology’).