Crystal structure of rat peroxisomal multifunctional enzyme type-1 complexed with 2E,4E-decadienoyl-CoA, 3R-hydroxy-4E-decenoyl-CoA and NAD

Crystal structure of rat peroxisomal multifunctional enzyme type-1 complexed with 2E,4E-decadienoyl-CoA, 3R-hydroxy-4E-decenoyl-CoA and NAD Descriptor: (S)-3-HYDROXY-(E)-4-DECENOYL-COA, 2E,4E-decadienoyl-CoA, GLYCEROL, ... Authors: Kiema, T.-R, Wierenga, R.K, Sridhar, S. Deposit date: 2026-02-03 Release date: 2026-07-22 Last modified: 2026-07-29 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural enzymological studies of multifunctional enzyme, type-1 (MFE1) with the 2E-decenoyl-CoA and 2E,4E-decadienoyl-CoA substrates: The regeneration of the dehydrogenase catalytic site is the rate limiting step of its combined reactions. J.Struct.Biol., 218, 2026