Anti-tumor activity of regorafenib alone and in combination against pediatric xenografts

CR, complete regression; PR, partial regression; TGD, tumor growth delay; TGI, tumor growth inhibition; 5xVi, Time to reach five time initial tumor volume; TD, tumor doubling time; TFS, tumor free survivor at day 120; ns, non-significant; Statistical analysis was performed using the non-parametric Mann-Whitney test for experiments with 2 treatment groups and the Kruskal-Wallis test for those with more than 2 groupsAnti-tumor activity of regorafenib alone and in combination against pediatric xenografts