Access to Polyfunctionalized Chiral Piperidines through Enantioselective Addition–Carbocyclization Cascade Reaction Catalyzed by a Rhodium(I)–Diene Complex
收藏Figshare2016-02-12 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Access_to_Polyfunctionalized_Chiral_Piperidines_through_Enantioselective_Addition_Carbocyclization_Cascade_Reaction_Catalyzed_by_a_Rhodium_I_Diene_Complex/2112592
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A new addition–carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous stereogenic centers were obtained with excellent enantio- and diastereoselectivities.
创建时间:
2016-02-12



