Additional file 1: of modPDZpep: a web resource for structure based analysis of human PDZ-mediated interaction networks
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All Supplementary tables are merged into single Excel file. Table S1. ROC- and PR-AUC values for 14 Human PDZ domains with artificial negative interaction data. Approximately equal number of binder and nonbinder were considered in small sets and average AUC is calculated for each domain. For SCRIBBLE1_LAP4_3, PSCDBP and NHERF2_2, equal number of non-binder peptides were randomly selected and AUC is calculated. This is repeated twice to get average AUC. Table S2. List of 43 PDZ domains included in modPDzpep testset. PDZ domains which cannot be predicted by POW are marked as ‘N’, while those used in the training are marked ‘T’. The list of test set peptides for these 43 PDZ domains is available under Benchmark link of modPDZpep server. Table S3. List of phage display peptides which showed exact match in human C-terminal proteome Table S4. Amino acid variants present on human PDZ domains. (XLS 55 kb)
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2016-12-15



