Risk of Primary gallbladder cancer in relation to quintiles of metabolic factors (n = 575,390).

1Quintile levels grouped by cohort and sex and for glucose, cholesterol and triglycerides further by fasting time. RRs were estimated from Cox regression models with attained age as time scale after excluding the first year after baseline measurement.
2RRs were adjusted for smoking status and age at baseline, stratified by cohort, sex and categories of birth year. RRs are corrected for regression dilution bias by use of the regression dilution ratio (RDR); conversion into uncorrected RR  =  exp (log (RR)*RDR). RDR: BMI, 0.90; mean blood pressure, 0.54; glucose, 0.28; cholesterol, 0.66; triglycerides, 0.51. Glucose and triglycerides were logarithmically transformed.
3RR were further adjusted for quintiles levels of BMI (except in BMI analysis).
§value missing for 1 case.
§§ value missing for 4 cases.
Abbreviations: RR, relative risk; SD, standard deviation; BMI, body mass index; Mid BP, mean blood pressure; RDR, regression dilution ratio