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Methyl-CpG-binding domain (MBD) sequencing of 45 primary neuroblastoma tumors

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NIAID Data Ecosystem2026-04-25 收录
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The DNA methylome of 45 primary neuroblastoma tumors is profiled by enrichment with a methyl-CpG-binding domain (MBD) and massively parallel sequencing DNA of 45 primary tumors is sheared (fragments of ± 200 bp), followed by MBD-based (MethylCap kit of Diagenode) enrichement, library preparation and multiplexing. Both input DNA and captured DNA were sequenced paired-end on Illumina Hiseq2000

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2019-07-03
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