VRK1 in complex with the inhibitor MP-60

VRK1 in complex with the inhibitor MP-60 Descriptor: (5Z)-3-butyl-5-[(3,5-dichloro-4-hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, 1,2-ETHANEDIOL, 2-(2-azanylethanoylamino)ethanoic acid, ... Authors: Aroucha, J.P, Crowley-Dolen, E.K, Mitchison, T.J, Massirer, K.B, Borges, R.J. Deposit date: 2025-12-06 Release date: 2026-04-29 Last modified: 2026-05-13 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structure-based discovery of selective vaccinia-related kinase 1 inhibitors and fluorogenic active-site probes. J.Biol.Chem., 302, 2026