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Crystal structure of haspin (GSG2) in complex with MU1668

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Protein Data Bank Japan2025-03-26 更新2026-04-19 收录
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Crystal structure of haspin (GSG2) in complex with MU1668 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine, GLYCEROL, ... Authors: Chaikuad, A, Paruch, K, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2024-06-04 Release date: 2024-09-11 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Thieno[3,2-b]pyridine: Attractive scaffold for highly selective inhibitors of underexplored protein kinases with variable binding mode. Angew.Chem.Int.Ed.Engl., 64, 2025
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2024-06-04
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