Relation of estimated glomerular filtration rate to prediction of all-cause mortality and cardiovascular events of the men and women, aged 35-74 years, free of previous cardiovascular diseases.

Estimated glomerular filtration rate (eGFR) by Chronic Kidney Disease Epidemiology Collaboration;
Due to the U shape of the association between eGFR and risk of death or CVD, Cox models were performed with the exclusion of persons with eGFR ≥ 109 mL/min/1.73m2;
*Hazard ratio with level 1 standard deviation (std) higher: all eGFR standard deviation (SD) 11.2, age 35-59 eGFR SD 9.3, age 60-74 eGFR SD 11.6;
All cause mortality models were adjusted for age (except those stratified by age classes), gender, current smoking , fasting glycemia, systolic blood pressure.
Incident cardiovascular diseases models were adjusted for age (except those stratified by age classes), gender, current smoking , fasting glycemia, systolic blood pressure and total cholesterol.