The List of Qualified and Regulated Proteome from Microvesicle-enriched Plasma <i>^a.</i>

aThe list contains quantitative information of the selected proteins from bias and background corrected iTRAQ data set. The denominator is the demographically matched control. Unused and %coverage are parameters related to the confident identification of proteins. This list contains 43 candidates qualified (out of 183) through the initial filters [i.e., unused prot score >3.0 and FDR = 1.1% (confident identification), p-value <0.05 (significantly different from 1) for at least one ratio]. The Significant ratios are indicated in bold. The uniport accession numbers of the ‘unreviewed’ proteins are indicated in italics form. The protein whose evidence is available only at the level of transcript is not provided with a gene symbol. The last column provides information about GO or pathway. CCC = complement and coagulation cascade, ECS = extracellular space, EIA = enzyme inhibitor activity, FA = focal adhesion, IIR = innate immune response, LT = lipid transport, RTW = response to wounding. *Reported as microvesicle or exosome marker by independent studies.