Additional file 4 of Genomic analysis of PLNTY-like tumor progression into epithelioid glioblastoma: a case report

Additional file 4: Table S3. Point mutations detected in the coding regions of the genes in both PLNTY-like tumor and three E-GB samples or in all three E-GB samples, but not in PLNTY-like tumor. The table presents information of the variant location, altered nucleotide and amino acid, functionality, and type of exonic mutation (non-synonymous, synonymous/ frameshift deletion). Number of altered DNA reads, total number of DNA reads and alteration fraction are also reported in all samples (PLNTY-FFPE, E-GB FFPE, E-GB FF and E-GB CL). Number of altered RNA reads, total number of RNA reads and alteration fraction is also reported in E-GB FF and E-GB CL samples. Additionally, the table provides information on whether variant is reported in ClinVar database, Cosmic database, allele frequencies in different populations and prediction scores for variant to be harmful in different prediction algorithms.