DNA methylation restricts default deterministic fates towards neural and germline lineages during early development
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214458
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We investigate the impact of DNA methylation on chromatin accessibility during epiblast differentiation. To this end, we used in vitro Epiblast-like cell (EpiLC) differentiation on WT and DNA-methylation free TKO murine ESCs. We next performed ATAC seq using TDE1 Tn5 transposase (Nextera). ATAC-seq on WT and TKO ESCs (D0), and D2, D4 EpiLCs
创建时间：
2024-07-02
