Dataset on the effect of vancomycin on metabolic changes in normal control mice

Here we treated normal control mice with vancomycin to disturb the gut microbiota and host metabolic phenotype. In order to study the effect of vancomycin on host metabolism, a 1H NMR-based metabolomics approach was applied to analyze metabolic changes in faecal sample of normal control (CON) and vancomycin-treated normal control diabetic (CONV) mice at 3, 7 and 11 weeks. This study is submitted to Microbiome. Hong Zheng, Pengtao Xu, Qiaoying Jiang, Qingqing Xu, Yafei Zheng, Junjie Yan, Hui Ji, Jie Ning, Xi Zhang, Chen Li, Limin Zhang, Yuping Li, Xiaokui Li, Weihong Song, and Hongchang Gao. (2021). Depletion of acetate-producing bacteria from the gut microbiota facilitates cognitive impairment through the gut-brain neural mechanism in diabetic mice.