Sequencing of chimeric deletion junctions
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1117804
下载链接
链接失效反馈官方服务：
资源简介：
To investigate the impact of spatial proximity on CRISPR-induced structural variant formation, sgRNAs were designed to target topologically associated domains (TADs) on the chromosomes 2, 6, 10, 17, 21 and X. The sgRNAs were paired to generate two double-strand breaks by CRISPR/Cas9. PCR amplicons from chimeric deletion-junctions were sequenced on the Illumina MiSeq platform (Eurofins Genomics, Germany) to investigate the composition of the ligation sites. Authors: M. Dahl-Jessen, T. Terkelsen, R. O. Bak, and U. B. Jensen.
创建时间：
2024-05-29
