Human Cervical Vagus Nerve µCT Dataset from Nodose Ganglion to Superior Cardiac Branch with Tissue Segmentations and 3D Reconstruction
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This dataset provides a high-resolution micro-computed tomography (µCT) image stack, tissue segmentation masks, and reconstructed 3D surface models of a single right human cervical vagus nerve, spanning the anatomical region from the nodose ganglion to the superior cardiac branch. A right human vagus nerve was collected post mortem from a body donor, fixed, and imaged by µCT to characterize its microanatomical and fascicular organization. The data support reconstruction of the nerve's fascicular architecture and the development of image-based, anatomically informed computational models of extracellular nerve stimulation for optimizing the selectivity of vagus nerve stimulation. Imaging. Micro-CT at 6.43 µm isotropic voxel size; slices 2864 × 2864 px, 16-bit. The nerve was imaged in five consecutive, anatomically adjacent segments along its length (nodose ganglion → superior cardiac branch). Segmentation. The human cervical vagus is multifascicular; per-slice masks delineate the epineurium and endoneurium relative to background, and the reconstructed surfaces are provided as separate epineurium and endoneurium 3D models. Contents (approximately 65 GB; formats .dcm, .stl), organized in the SPARC SDS layout: source/<segment>/img/ — raw µCT DICOM image stacks (segments 795, 796, 797, 798, 813). derivative/<segment>/mask/ — DICOM segmentation masks aligned 1:1 with the image stacks. derivative/epineurium.stl, derivative/endoneurium.stl — reconstructed 3D surface models. dataset_description.xlsx, manifest.xlsx, subjects.xlsx, samples.xlsx, submission.xlsx — SPARC SDS metadata.



