Expression data from sorted humanized TREM2 murine microglia
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
The R47H variant of TREM2 is associated with higher risk of Alzheimer's disease. We generated mice expressing the common variant or R47H variant of human TREM2 in the absence of murine TREM2 on the 5XFAD mouse model of Alzheimer's disease. CD45+ CD11b+ microglia were sorted from brains of 8.5-month-old mice expressing common variant, R47H, or no human TREM2 on a background of murine TREM2 deficiency and the 5XFAD mouse model of Alzheimer's disease.
创建时间：
2019-03-04
