Haplotype association analysis of CRYBA4 SNPs for the replication sample set.

*Haplotypes are indicated in both the ACGT and the 1–2 (major-minor allele) formats. Haploview defines 3 haplotype blocks: Block 1 (S1-S2-S3-S4), Block 2 (S5-S6-S7-S8-S9) and Block 3 (S10-S11), where S1 = rs5761635, S2 = rs2283843, S3 = rs5997109, S4 = rs2071860, S5 = rs2071861, S6 = rs2071862, S7 = rs4276, S7 = rs2239832, S8 = rs5752359, S9 = rs2009066, S10 = rs1018833, and S11 = rs739310. For details, see Figure 1. For haplotype analysis by Plink, this table shows the best sliding window only; the best sliding window consists of two SNPs (S8 = rs5752359, S9 = rs2009066). SNPs S8 and S9 are underlined for the sake of easy cross referencing between Haploview-defined block 2 and Plink’s best sliding window.†Nominal P value is indicated as Pnom while empirical p value generated by 10,000 permutations is indicated as Pemp.