Pneumonia in Myasthenia Gravis: Microbial Etiology and Clinical Management

Patients with myasthenia gravis (MG) are prone to the development of pneumonia due to long-term immunotherapies and the tendency for aspiration. Pneumonia remains a risk factor for MG worsening and even the most prevalent cause of mortality in MG patients. The pathogen classification and the exploration of the risk factors for mechanical ventilation (MV) may aid in improving the clinical outcome. Between January 2013 and October 2022, an inpatient database review for MG patients with pneumonia concurrence was performed in a tertiary research center for neuromuscular disorders. Our identification of the microbial etiology of pneumonia in MG patients may provide future perspectives on accurate antibiotic options and early interventions of the risk factors are of paramount importance to improve the clinical outcome.