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A unique chromatin complex occupies young alpha-satellite arrays of human centromeres

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NIAID Data Ecosystem2026-03-11 收录
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Using high-resolution chromatin immunoprecipitation (ChIP) of centromere components and clustering of sequence data we find that specific dimeric alpha-satellite units shared by multiple individuals dominate functional human centromeres. We have analyzed the chromatin landscape of the human genome using paired-end MNase-seq

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2019-05-15
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