Excess SeMet is cleaved into MeSeH by PXLP-K212-CTH
收藏reactome.org2025-01-21 收录
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Excess selenomethionine (SeMet) undergoes an alpha,gamma-elimination reaction by cystathionine gamma-lyase (CTH) to produce methylselenol aka methaneselenol (MeSeH), ammonia, and 2-oxobutanoic acid. This reaction is inferred from the event in mouse involving the protein cystathionine gamma-lyase (Cth) (Okuno et al. 2001, Okuno et al. 2005, Okuno et al. 2006).
过量的硒蛋氨酸(SeMet)在胱硫醚-γ-裂解酶(CTH)的作用下,通过α,γ-消除反应生成甲基硒醇(又称甲硒醇,MeSeH)、氨和2-氧代丁酸。该反应由涉及蛋白胱硫醚-γ-裂解酶(Cth)的鼠类事件推断而来(Okuno 等人,2001年,Okuno 等人,2005年,Okuno 等人,2006年)。
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