eIF3 is a multi-subunit complex thought to execute numerous functions in canonical translation initiation, including mRNA recruitment to the 40S ribosome, scanning for the start codon, and inhibition

NIAID Data Ecosystem40

CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis

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CASP9 (caspase 9) is a well-known initiator caspase which triggers intrinsic apoptosis. Recent studies also suggest various non-apoptotic roles of CASP9, including macroautophagy/autophagy regulation.

DataCite Commons2021-05-08 更新70

ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance

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Pluripotent stem cells, including induced pluripotent and embryonic stem cells (ESCs), have less developed mitochondria than somatic cells and, therefore, rely more heavily on glycolysis for energy pr

DataCite Commons2020-09-03 更新50

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

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