Microwave-Assisted Regioselective Synthesis of 3‑Functionalized Indole Derivatives via Three-Component Domino Reaction
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A microwave-assisted regioselective synthesis of 3-functionalized indole derivatives via a three-component domino reaction of anilines, arylglyoxal monohydrates, and cyclic 1,3-dicarbonyl compounds is described. The main advantages of this protocol are short reaction times, practical simplicity, its metal-free nature, the availability of starting materials, green solvents, and high regioselectivity.
创建时间:
2017-11-02



