Nicotinic Acid Receptor GPR109A Is Down-Regulated in Human Macrophage-Derived Foam Cells
收藏Figshare2016-01-18 更新2026-04-29 收录
下载链接：
https://figshare.com/articles/dataset/_Nicotinic_Acid_Receptor_GPR109A_Is_Down_Regulated_in_Human_Macrophage_Derived_Foam_Cells_/696226
下载链接
链接失效反馈官方服务：
资源简介：
Nicotinic acid (NA) regresses atherosclerosis in human imaging studies and reduces atherosclerosis in mice, mediated by myeloid cells, independent of lipoproteins. Since GPR109A is expressed by human monocytes, we hypothesized that NA may drive cholesterol efflux from foam cells. In THP-1 cells NA suppressed LPS-induced mRNA transcription of MCP-1 by 76.6±12.2% (P
创建时间：
2016-01-18
