Effect of hematopoietic Tet2 deletion on steatohepatitis. Effect of hematopoietic Tet2 deletion on steatohepatitis

NIAID Data Ecosystem2026-03-14 收录

脂肪性肝炎

造血调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA927295 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2023-01-25

Effect of hematopoietic Tet2 deletion on bulk liver gene expression in a mouse model of steatohepatitis [bulk]. Effect of hematopoietic Tet2 deletion on bulk liver gene expression in a mouse model of steatohepatitis [bulk]

脂肪性肝炎

基因表达分析

To investigate the role of hematopoietic Tet2 loss on the development of steatohepatitis, mice were transplanted with wild type or Tet2 deficient bone marrow cells and fed a choline-deficient, L-amino

NIAID Data Ecosystem40

Using single-cell RNA-Seq for unbiased analysis of developmental hierarchies (single cell RNA Seq of Irf8 KO GMP). Mus musculus

单细胞转录组学

造血调控

Single cell RNA seq and bioinformatic analysis is used to characterize myeloid differentiation to uncover novel transcriptional networks and key drivers of hematoipoietic development Overall design: S

NIAID Data Ecosystem20

Investigating the Role of Intestinal TM6SF2 Knockout in Metabolic Dysfunction-associated Steatohepatitis

脂肪性肝炎

肠道-肝脏轴代谢

Metabolic dysfunction-associated steatohepatitis (MASH)is a complex disease involving genetic predisposition and gut microbiota. However, how such host gene-microbiota interactions contribute to MASH

NIAID Data Ecosystem10

SCL establishes a global repressive environment and cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells [ChIP-seq]

造血调控

表观遗传学

Understanding the molecular basis of cell fate decision is critical to shed light onto biological processes supporting tissue formation. In particular, whether lineage-fated cells derive from multi-pr

NIAID Data Ecosystem30

Using single-cell RNA-Seq for unbiased analysis of developmental hierarchies (single cell RNA Seq of bone marrow lineage-negative Sca1+ CD117+ cells). Mus musculus

单细胞转录组学

造血调控

NIAID Data Ecosystem10