Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

NIAID Data Ecosystem2026-05-01 收录

抗病毒药物

冠状病毒抑制剂

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Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

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2023-10-18

Supporting data for "The antiviral potential of an arginine depletion agent in influenza viruses and human coronaviruses" .

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病毒学实验数据

All raw data for "The antiviral potential of an arginine depletion agent in influenza viruses and human coronaviruses". Files are categorised based on the type of experiment. Dataset includes mostly i

DataCite Commons2023-09-21 更新120

Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease

基于结构的药物设计

冠状病毒抑制剂

Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease

NIAID Data Ecosystem60

Inhibition of SFV and SINV replication by selected hit compounds measured by CPE reduction and virus production assays.

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病毒复制抑制

aIC50 values against SFV and SINV were determined in dose-response experiments using an assay for the reduction of cytopathic effect. A concentration range from 200 µM to 0.1 µM was applied for each c

Figshare2015-12-02 更新50

Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 1c

冠状病毒抑制剂

抗病毒药物结构与结合机制

Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 1c Descriptor: 3C-like proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-({[(1R,2R)-2-pheny

Protein Data Bank Japan2024-11-20 更新100

Relationship between infectivity and genomic RNA copies.

病毒复制定量

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Data are sumarized as mean ± SD (3 to 6 determinations). Drug treatments used: 10 mM NH4Cl, 10 nM Concanamycin A, or 25 µM furin inhibitor. Control indicates that no drug was added to the culture medi

NIAID Data Ecosystem60

Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

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