Incidence of abnormal spindles in Hdac mutant MII eggs.

Difference between WT and mutant is significant, *P<0.05, **P<0.01, χ2. The difference between Hdac2−/−and Hdac1−/+Hdac2−/− MII eggs is also significant, P<0.05.

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Incidence of aneuploidy in Hdac1 −/+ /Hdac2 −/− and Hdac2 −/− eggs.

*p<0.01. The difference between Hdac1−/+/Hdac2−/− and Hdac2−/− eggs is not significant.

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Quantification of parasite eggs.

Background Infections caused by soil-transmitted helminths (STHs) are the most prevalent neglected tropical diseases and result in a major disease burden in low- and middle-income countries, especiall

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