Comparison of bulk RNAseq results of WT and TKO E14 NPCs

We investigate the impact of DNA methylation on neural somatic differentiation. To this end, we used in vitro neural progenitor cell (NPC) differentiation on WT and DNA-methylation free TKO murine ESCs. We next performed bulk RNAseq at D0, D2, D4, D6 and D8 of differentiation to study transcriptomic differences. Bulk mRNA sequencing on WT and TKO ESCs (D0), and D2, D4, D6 and D8 cells during NPC differentiation