A375 melanoma cells treated with leflunomide 25uM. Homo sapiens

NIAID Data Ecosystem2026-03-07 收录

药物转录组学

黑色素瘤药物研发

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA132661 数据链接链接失效反馈

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资源简介：

Human A375 melanoma cells were treated with leflunomide 25uM for 3 days, then RNA harvested Overall design: 6 arrays

创建时间：

2011-03-30

A novel Chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products

黑色素瘤药物研发

ROS诱导DNA损伤

Melanoma is one of the most aggressive tumors with the remarkable characteristic of resistance to traditional chemotherapy and radiotherapy. Although targeted therapy and immunotherapy benefit advance

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Bulk RNA-seq comparison of TYA018 HDAC6 inhibition vs vehicle after a single dose treatment in Mus Musculus to treat heart failure with preserved ejection fraction

HFpEF治疗机制

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Heart failure with preserved ejection fraction (HFpEF) is a prevalent health condition associated with high morbidity and mortality, but currently, there are few effective therapies. Our previous rese

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Microarray Expression Profiling of Punicalagin, Myricetin and Quercetin Treated Leukemia Cell Line (THP-1)

药物转录组学

白细胞基因表达

THP-1 monocyte were differentiated to macrophage using PMA for 24 hrs, then (THP-1) macrophage were treated with DMSO, Punicalagin, Myricetin or Quercetin for 24 hrs. Transcriptional expression profil

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Transcriptomic data of the project "Optimisation of PK/PD parameters of a repurposed drug therapy for patients with SMA"

脊髓性肌萎缩症

药物转录组学

Characterisation of the transcriptome of the spinal cord and quadriceps of delta 7 mice treated with haloperidol (NIH BioProject Accession number: PRJNA1251322) and hiPSC-motoneurons derived from pati

Zenodo2026-03-11 更新20

Transcriptomic Analysis of Control and PLX4032 Resistant Clones with RNA Sequencing

黑色素瘤药物研发

转录组分析

NGS-derived transcriptome profiling (RNA-seq) of control and PLX4032 resistant clones to identify resistance-associated gene-expression changes and pathway enrichments, and to integrate with exome and

NIAID Data Ecosystem00

A375 melanoma cells treated with leflunomide 25uM. Homo sapiens

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