Supplementary Information: RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity
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The Simulation_files folder contains initial coordinates, input files and output coordinates of the Molecular Dynamics (MD) simulations of wild type and mutants of the Apdp peptide in the ribosome ( region of 35 Å around the peptide). The Uncharged_N-terminal_residues folder includes residue topologies (.rtp file) and hydrogen data bank (.hdb) of the uncharged terminal Alanine and Proline (used for modelling Ala134 and Pro134). The Figures folder contains rmsd, distances, rmsf values, and projections on the most dominant conformational modes sampled by the Ala 132 backbone atoms obtained from the MD trajectories.
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Zenodo创建时间:
2023-12-23



