Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
收藏Protein Data Bank Japan2023-11-15 更新2026-03-21 收录
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Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. Descriptor: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-14-{4-[BENZYL(METHYL) AMINO]-4-OXOBUTANOYL}-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN-16-OIC ACID, ... Authors: Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A, Mikolajczyk, J, Salvesen, G.S, Gruetter, M.G, Powers, J.C. Deposit date: 2005-09-29 Release date: 2006-09-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
创建时间:
2005-09-29



