Summary statistics for genetic instruments used in single-trait MR analyses.

Lipid exposure summary statistics are from the MVP European data set and BC summary statistics from the BCAC consortium meta-analysis. SNP: rsID of genetic instrument; exposure: lipid trait for exposure statistics; effect_allele.exposure: allele used for lipid and BC effect estimates; other_allele.exposure: noneffect allele; beta.exposure: effect size estimate for lipid trait; se.exposure: standard error of lipid effect size estimate; pval.exposure: P-value of lipid trait effect estimate; beta.bc: effect size estimate of BC risk; se.bc: standard error of BC risk effect estimate; pval.bc: P-value for BC risk effect estimate; inclPruned: logical, was SNP included in pruned single-trait MR analysis. BC, breast cancer; BCAC, Breast Cancer Association Consortium; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MR, Mendelian randomization; MVP, Million Veteran Program; TC, total cholesterol; TG, triglyceride. (XLSX)