plasma energy metabolomics in patients with ocular disease

Energy metabolism, or central carbon metabolism, encompasses processes that generate adenosine triphosphate (ATP) from nutrients through aerobic and anaerobic respiration, supporting essential cellular functions. Quantifying energy metabolism not only provides insight into cellular energy management but also allows for the investigation of metabolite flux within these interconnected pathways. mitochondrial dysfunction and energy metabolism disruptions have been observed in glaucoma, including altered mitochondrial substrates, gene mutations, and structural abnormalities, a comprehensive energy metabolomics analysis in POAG has yet to be undertaken to illustrate the alterations in the energy metabolism landscape.