Effect of GSK3 inhibition on the transcriptional signature of human monocytes
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE256538
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资源简介：
We explored the molecular impact of blocking GSK3 on the gene expression profile in human monocytes. GSK3 inhibition by CHIR-99021 redirected monocytes towards acquiring an anti-inflammatory gene profile similar to M-CSF-primed monocyte-derived macrophages. mRNA profiles of purified human monocytes treated DMSO or 10 micromolar of GSK3a/β inhibitor (CHIR99021) or 10 ng/mL M-CSF for 16 hours.
创建时间：
2025-07-16
