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Crystal structure of TEAD1-YBD in complex with K-975

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of TEAD1-YBD in complex with K-975 Descriptor: N-[3-(4-chloranylphenoxy)-4-methyl-phenyl]propanamide, Transcriptional enhancer factor TEF-1 Authors: Tsuji, Y, Suzuki, M, Yasunaga, M, Hamguchi, K, Saito, J. Deposit date: 2020-07-28 Release date: 2021-02-03 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.5 Å) Cite: The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma. Am J Cancer Res, 10, 2020

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2020-07-28
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