The multiomics data on gametes and early embryos in bovine and porcine Raw sequence reads. The multiomics data on gametes and early embryos in bovine and porcine

Small-scale in situ High-through chromosome conformation capture Hi-C (sis-Hi-C) for the 3D architecture of genomes in GV oocytes, 4-cell embryo, 8-cell embryo, Blastocyst, ama treatment 4-cell embryo and ama treatment 8-cell embryo.To investigate the effect of Pol II on the initiation of early mammalian embryonic development, we analyzed Pol II in bovine gametes and embryos at different stages with Small-scale Tn5-assisted chromatin cleavage with sequencing (Stacc-seq), and examined the enrichment and binding sites of transcription factors. The results showed that Pol II clusters play an important role in regulating ZGA gene expression and embryogenesis.