Animals were scored for presence of nuclear puncta after treatment with DMSO, daf-2(RNAi), FLA or following a 2 hour heat-shock incubation at 37°C. A Student's T-Test was used to determine statistical
The liver is the central organ for carbohydrate metabolism to maintain the blood glucose concentration within a normal range. Glucose breakdown or synthesis in the liver is tightly regulated by insuli
microRNAs are small non-coding RNAs that can affect gene expression. We used microarrays to analyze gene expression in miR-499 transgenic mouse hearts. Overall design: Cardiac ventricles were collecte
C. elegans DAF-16/FOXO phosphorylation in different genetic backgrounds was analyzed by mass spectrometry of affinity purified HA-tagged DAF-16. Genetic backgrounds studied include par-1 hypomorphic m
