Summary of NLuc fusion protein constructs and ASO/BRET binding affinities.

Gene ID of full length protein is given. For certain proteins the full length protein was not cloned and the domains included in the NLuc fusion are indicated in parentheses. Known nucleic acid binding domains: RNA binding domain (RBD), DNA binding domain (DBD), Hybrid binding domain (HBD). KD’s (nM) for 5-10-5 2’F (766638), cEt (766636) and MOE (766634) gap-mer ASOs were determined using GraphPad Prism software.