Whole genome analysis of Staphylococcus aureus carrying a mobile DNA with a new transposition mechanism. Staphylococcus aureus

Staphylococcus aureus is a most common pathogen that threatens the lives of patients and health of individuals not only in hospitals but also in the community. S. aureus causes skin and soft tissue infections such as bullous impetigo, furunculosis, and staphylococcal scalded skin syndrome; life-threatening infections such as blood-stream infections, pneumonia and toxic shock syndrome. There are divergent global S. aureus lineages, and S. aureus evolution includes horizontal gene transfer, mediated by, for example, mobile DNA elements. In this study, we investigated the whole genome of S. aureus, which contained multiple copies of a mobile DNA, focusing on the new mechanisms, through which mobile DNAs can efficiently be transposed.