Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Improved Feline Drugs as SARS-CoV-2 Mpro Inhibitors: Structure-Activity Studies & Micellar Solubilization for Enhanced Bioavailability Descriptor: 3C-like proteinase, N~2~-{[(3-fluorophenyl)methoxy]carbonyl}-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide Authors: Khan, M.B, Arutyunova, E, Young, H.S, Lemieux, M.J. Deposit date: 2021-01-11 Release date: 2022-12-07 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Improved SARS-CoV-2 M pro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. Eur.J.Med.Chem., 222, 2021
创建时间：
2021-01-11
