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Candida albicans Cells: Control vs. BDSF (Cis-2-dodecenoic acid) treatment

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137546
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Cis-2-dodecenoic acid (BDSF), a signalling molecule produced from burkholderia cenocepanic, can prevent C. albicans hyphal and biofilm formation. The mechanism of how BDSF controls C. albicans morphological switch is still unknown. To address this issue, we used DNA microarray method to investigate the changes in gene expression before and after BDSF treatment. Further, screening a mutant library based on microarray data was carried out to find the mutants unresponding to BDSF. Two-condition experiment, control vs. BDSF treatment. Biological replicates: C1 and C2 are control group, B1 and B2 are BDSF treatment group. One replicate per array.
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2020-03-16
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