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Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress

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NIAID Data Ecosystem2026-03-12 收录
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Here we report Total RNA seq and RiboSeq on MEF cells treated with halofuginone. Halofuginone is a competitive inhibitor of the Prolyl-tRNA synthetase that results in an accumulation of uncharged Prolyl-tRNA upon treatment that leads to an activation of the protein kinase Gcn2. Overall design: Total RNA Seq and ribosome footpinting in halofuginone and untreated MEF cells

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2021-05-29
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