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Shotgun lipidomics of mouse liver with adenovirus mediated PNPLA3 overexpression in ATGL-/- mice.

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DataCite Commons2023-11-07 更新2024-08-18 收录
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https://figshare.com/articles/dataset/Shotgun_lipidomics_of_mouse_liver_with_adenovirus_mediated_PNPLA3_overexpression_in_ATGL-_-_mice_/24518665
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10-week-old female C57BL/6J whole-body ATGL-/- mice were maintained on chow diet and infected with Ad-null, Ad-FLAG-PNPLA3-WT virus via retroorbital injection at 5x10^8 PFU/mouse. Four days post-injection, mice were sacrificed following a 12-h fast.Total lipids were extracted from mouse liver tissues and analyzed using multidimensional mass spectrometry (MDMS)-based shotgun lipidomics (MDMS-SL) at the University of Texas Health Science Center at San Antonio, as previously detailed (Yang et al., Anal.Chem., 2009)Ad-null group: 1300, 1301, 1338Ad-PNPLA3-WT group: 1261, 1282, 1289
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figshare
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2023-11-07
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